DENSS

DENsity from Solution Scattering

Welcome to DENSS.org

DENsity from Solution Scattering

About DENSS

About DENSS

DENSS is an algorithm for calculating 3D particle electron densities directly from 1D solution scattering data.

Get DENSS

Download DENSS from GitHub and get instructions for installation, how to use it, and tips and best practices.

DENSSWeb

Try DENSS out. Simply upload your data to our online server to get a fully averaged reconstruction in just a few minutes.

Latest Updates…

New DENSS Video Tutorial

Filed Under: News

Interested in trying out DENSS? There is now a video tutorial describing the algorithm behind DENSS, how to download and install DENSS, and how to use DENSS. This video was done in collaboration with SBGRID's YouTube … [Read More...]

New MEMBRANE mode

Filed Under: Developments, News

DENSS now has a new mode for membrane proteins. Membrane proteins are often solubilized in detergents or lipid nanodiscs. The hydrophobic regions of these molecules often have lesser scattering density than the bulk … [Read More...]

New symmetry averaging feature

Filed Under: Developments, News

DENSS now includes the ability to impose symmetry to improve the resolution of reconstructions. DENSS first aligns the principal axes of the map with the x, y, and z axes. Then the value of the map at each symmetry mate … [Read More...]

Contact the Author:

  • Email
  • Phone
    (716) 898-8675
  • Address
    Hauptman-Woodward Institute
    700 Ellicott Street
    Buffalo, New York, USA 14203