DENSSWeb, our online web server for running the full DENSS pipeline, has recently received a major update. Try out DENSSWeb at denss.ccr.buffalo.edu
DENSSWeb runs 20 individual DENSS reconstructions and aligns and averages the reconstructions. DENSSWeb now has the Fast, Slow, and Membrane modes available. Previously only Fast mode was available for quick reconstructions of simple systems, and now DENSSWeb is capable of producing results suitable for publication with the additional Slow and Membrane modes for most particles.
DENSSWeb can take now multiple input files, including the ability to automatically fit raw data and estimate Dmax. DENSSWeb has three possible modes: Fast (~10 minutes), Slow (default, ~30 minutes), and Membrane (for particles with negative contrast, ~30 minutes). Options for Symmetry averaging are also now available.
LiteMol is used to display a web-based, interactive viewer of the final averaged density using four different isocontour levels to illustrate the internal density variations present in the particle.
DENSSWeb is maintained and supported by the DENSS authors and the Center for Computational Resources.