One of the problems with solution scattering is that enantiomers (mirror images of a particle) yield identical scattering profiles. For some particle shapes this can prove to be a serious problem resulting in opposite enantiomers being averaged during the averaging procedure. The superdenss script now includes a new option (-e) that can be used to generate all possible enantiomers for each reconstruction of denss.py and select the enantiomer that best fits the reference model. To learn how to … [Read more...]
DENSSWeb goes live
The online server DENSSWeb is now available for researchers to upload their data and perform calculations with DENSS, including full averaging with EMAN2. DENSSWeb includes an interactive viewer for visualizing the averaged electron density map in 3D using LiteMol. DENSSWeb is also a web-based front end graphical interface that can be downloaded for personal use to perform more advanced calculations in a convenient manner, including the interactive viewer. To use DENSSWeb, visit … [Read more...]
DENSS published in Nature Methods
The algorithm behind DENSS was published online in the high-impact journal Nature Methods. With a 5-year impact factor of 35, Nature Methods remains one of the most high-impact academic journals in the world! … [Read more...]
DENSS.org goes live
DENSS.org is a website dedicated to the development and usage of DENSS, an algorithm for calculating electron density from solution scattering data. DENSS.org will contain the latest updates and developments and provide a central resource for the community for using the software. Instructions for installation and usage, tips, and best practices can all be found here. If you have any questions, send a message to the author below. … [Read more...]